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Together with an interdiziplinary team he uncovered the molecular mechanisms of Alzheimer's disease and identified target molecules for therapeutic treatment.
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81377 München christian.haass(at)dzne.de +49 89 4400-46549 Areas of investigation/research focus Prof. Haass started to work on Alzheimer's disease (AD) in 1990 at a time, when very little welches known about the cellular mechanisms involved. Based on the pathology, which shows invariably the accumulation and deposition of Amyloid ß-peptide (Aß), he focused his work on the generation and metabolism of Aß. Christian Haass hypothesized against the widely accepted general opinion hinein this field that Aß may Beryllium produced from its precursor hinein a physiologically weit verbreitet pathway and not necessarily in a pathological process. Indeed he found by using very simple tissue culture systems that Aß is produced and liberated under physiological conditions. This pivotal finding welches a major breakthrough for the entire field, since it allowed elucidating the molecular principles behind Aß generation as well as the identification of the enzymes (the so-called secretases) involved hinein generation and liberation of the peptide and finally the development of selective inhibitors to therapeutically lower Aß production in patients.
Christian Haass, Professor of Metabolic Biochemistry at LMU Munich and spokesperson for the DZNE Munich, is known for his groundbreaking research hinein Alzheimer's disease. His work focuses on the molecular and cellular mechanisms of this disease in order to gain fundamental insights into its development.
Momo’s Driving School in Munich also offers refresher courses for licence-holders World health organization want to optimise their driving skills or who have not driven for a long time and want to gather practical driving experience accompanied by a driving instructor.
Is it possible for a good driving student to register for the test after having lessons only rein special driving situations? No, that is not possible because of the legal regulations.
Next to the Ostfriedhof bus and tram stop Can I take a trial lesson rein the theoretical course rein order to get an impression of the atmosphere?
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On this page you will find all the information you need again in Modul; from there you can also fix an appointment online with your local citizen’s office.
When you have attended all the required theme-based theoretical classes, you take a pre-test (of about 10 minutes) during office hours at the driving school; if you make fewer than 10 mistakes, you will receive the Fortbildung certificate.
Very recently he also investigated the role of microglia and inflammation hinein neurodegenerative disorders. This work led to the spectacular finding that microglial phagocytosis may be impaired late during neurodegeneration and opened up a completely unexpected road towards new therapeutic developments for patients already developing disease symptoms. This work resulted rein the identification of TREM2 as a CSF marker for microglial activity. Rein a unique cohort of subjects with autosomal dominant AD, CSF sTREM2 was abnormally increased 5 Weiterlesen years before the expected onset of symptoms. This will not only greatly facilitate research on inflammatory disease overarching mechanisms, but may also provide a very valuable therapeutic marker.
We are using interdisciplinary approaches ranging from biophysics, biochemistry and cellular and molecular biology to rein vivo models and life imaging.
If you are lacking driving practice or simply haven't driven a car rein a long time and have got out of the habit, we can help you get back into it with a few refresher lessons.